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Clinical SDTM Programmer

ICON Plc -
Dublin, County Dublin

Apply Now

Job details

Full-time
4 days ago

Qualifications

Computer Science
XML
SAS
Data structures
Bachelor's degree
Communication skills

Full job description

Clinical SDTM Programmer (advanced)

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

We are recruiting an Advanced Clinical Programmer (SDTM) to support a long‑term FSP partnership with a global, top‑tier pharmaceutical company.

This role is highly focused on SDTM oversight, standards, and submission readiness, with direct visibility across study teams and regulatory deliverables.

About the Role

As an Advanced SDTM Clinical Programmer, you will provide end‑to‑end oversight of SDTM programming activities, from study set‑up through to submission‑ready packages. You will act as a technical authority on CDISC standards, ensuring quality, compliance, and consistency across trials while collaborating closely with Data Management, Statistics, and clinical teams.

This is an ideal opportunity for someone who enjoys SDTM governance, review, and strategic input, not just hands‑on programming.

Key Responsibilities

Provide expert oversight of SDTM programming activities from study start‑up through database lock and regulatory submission
Lead or review the development of submission‑ready CDISC SDTM packages, including aCRFs, define.xml, and cSDRGs
Review and contribute to trial set‑up documentation, including data transfer agreements, metadata, and trial design specifications
Create or review SDTM mapping specifications for internal and external data sources
Generate or oversee the creation of SDTM datasets using standardized conversion frameworks and utilities
Ensure high-quality, compliant datasets, including Pinnacle 21 review, readiness for interim analyses, medical review, and final lock
Program or oversee data quality checks and review reports to support Data Management and study teams
Maintain regulatory awareness, ensuring SDTM deliverables meet FDA, PMDA, and global submission requirements
Act as a subject matter expert across CDISC standards (SDTM, CDASH, controlled terminology, define.xml)
Support the development and implementation of programming standards within the organisation
At senior level: mentor junior or flexible resources and provide leadership or coordination of support teams where required

Key Interfaces

You will work closely with a wide range of stakeholders, including:

Clinical Programmers and Statistical Programmers
Clinical Trial and Data Management teams
Clinical Data Standards groups
External DM CRO partners
Enabling Business & Information Services (EBIS)

Required Experience & Skills

Bachelor’s degree (or higher) in Computer Science, Data Science, Mathematics, or a related scientific discipline (or equivalent experience)
Strong clinical programming background with hands‑on trial experience
Expert knowledge of SAS programming within a clinical research environment
Advanced expertise in CDISC SDTM, including aCRFs, define.xml, and cSDRGs
Deep understanding of clinical data structures (SDTM and working knowledge of ADaM)
Experience working in global, cross‑functional clinical research teams
Comfortable operating in a fast‑paced, matrixed FSP environment
Strong organisational, communication, and stakeholder management skills
Project oversight or coordination experience is highly desirable

Why Apply?

Long‑term stability through a strategic FSP partnership
Direct exposure to high‑impact regulatory submissions
Opportunity to operate as an SDTM standards and oversight expert, not just a producer
Collaborative, global environment with access to industry‑leading tools and standards
Clear pathway for senior technical influence and mentorship

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Apply Now

Refine Your Search

junior computer jobs in dublin, d

Clinical SDTM Programmer

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Project Engineer - Capital Maintenance

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