Find Lead site reliability engineer Jobs in Dublin, D

BDS Manufacturing Operations Lead
Alexion Pharmaceuticals,Inc. —Dublin, County Dublin
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Senior Java Developer - Coaching & Delivery
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Réalta Technologies (RT) —Dublin, County Dublin
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Senior Network Engineer
Workhuman —Dublin, County Dublin
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Network Development Engineer, Network - Core
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Critical Infrastructure Fire Protection Engineer (Field Engineering), Data Center Engineering
Amazon Development Centre Ireland Limited —Dublin, County Dublin
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Warranty Technician
ALSTOM —Dublin, County Dublin
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Automation Engineer - Utilities
NeoDyne —Dublin, County Dublin
- Overtime
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Cloud Platform Lead
SoftCo —Dublin, County Dublin
- Full-time
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Senior Software Engineer - API Platform (Python/Typescript)
Workday —Dublin, County Dublin
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Engineering Manager - Civil, Structures & Utilities
Dublin Port Company —Dublin, County Dublin
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Senior Developer, Agentic AI Engineering
Workday —Dublin, County Dublin
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Asset Management Utilities Engineering Technician(Plumber)
DAA —Dublin, County Dublin
- Full-time
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Sr. Automation Engineer - Packaging
Amgen —Dún Laoghaire, County Dublin
- €76,859.55–€103,986.45 a year
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Electrical Colocation Regional Engineer, Colo Regional Engineering
Amazon Data Services Ireland Limited —Dublin, County Dublin
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Director Cloud Platform
Guidewire Software —Dublin, County Dublin
- Weekend availability
- Doctoral degree
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BDS Manufacturing Operations Lead

Alexion Pharmaceuticals,Inc. -
Dublin, County Dublin

Apply Now

Job details

Qualifications

Doctoral degree
Engineering
Logistics
Master's degree
Bachelor's degree
Manufacturing
AI
Business
Leadership
Communication skills
Negotiation

Full job description

Location: Dublin, Ireland Job reference: R-255152 Date posted: 07/15/2026

Introduction to role:

Are you ready to lead end-to-end biologics drug substance manufacturing and build an operation that never wavers on safety, quality, and reliability? Do you want your decisions in Dublin to translate directly into consistent supply for patients living with rare and devastating conditions?

Based at our College Park, Dublin campus and reporting to the Senior Director, Operations, you will join the site’s Operations Leadership Team to set a clear vision for resilient, compliant, and efficient manufacturing. You will steer upstream and downstream operations through to product release, championing continuous improvement and seamless new product introductions. While you will deploy digital and AI tools where they deliver measurable value, your primary focus is rock-solid operations that safeguard product quality and patient safety.

This is a role for a decisive leader who thrives at the intersection of people, process, and performance—someone who can set direction, inspire teams, and deliver results under regulatory scrutiny and in a rapidly evolving portfolio.

Accountabilities:- Operational Resilience and Accountability: Establish and sustain robust, high-reliability processes with contingency readiness; proactively identify, mitigate, and escalate operational risks to uphold the highest standards of safety, quality, and compliance.- Digital and AI Integration: Evaluate and implement practical digital and AI solutions that improve yield, throughput, monitoring, and predictive maintenance; grow digital literacy across teams to embed new ways of working.- Team Leadership: Build, inspire, and retain a first-class manufacturing organization; set clear expectations, develop talent, and create a culture where safety, compliance, and continuous improvement are non-negotiable.- Cross-Functional Collaboration: Orchestrate seamless interactions with EHS, Quality Assurance, Engineering, Technical Services, and Supply Chain to remove barriers, align priorities, and deliver dependable production.- Change Leadership: Act as a visible change agent; mentor teams through organizational and process changes, build advocacy across the site and wider business, and ensure adoption sticks.- Production Performance and Sustainability: Own and communicate performance metrics; manage capacity and cycle times; drive initiatives that increase throughput, reduce variability, and deliver cost and sustainability gains.- Regulatory Excellence and NPI: Lead the site confidently through inspections, submissions, and licensure activities; ensure flawless tech transfers, new product introductions, and process improvements without disruption.- Stakeholder Communication: Provide timely, transparent updates on milestones, risks, and key decisions to senior and corporate stakeholders; bring data-driven insight and clear recommendations.- Financial Stewardship: Manage significant budgets with rigor; strengthen financial controls; deliver cost-efficient operations using proven methods and targeted digital enhancements.

Essential Skills/Experience:- Experience: Minimum 12 years in pharmaceutical or biopharmaceutical manufacturing operations, quality, and/or technical services, with a preference for biological drug substance experience and multi-area expertise.- Operational Resilience: Demonstrated ability to build resilient, high-performing operations and proactively manage risk, quality, and compliance at the highest standards.- People Leadership: Exceptional talent management and team-building experience, with strong motivational, communication, and negotiation skills.- Digital & AI Acumen: Practical experience with digital transformation and AI-enabled tools in operations; able to mentor staff in adopting new technologies as part of broader operational excellence.- Change Management: Clear evidence of successfully leading organizational change and supporting continuous improvement in dynamic, fast-paced environments.- Regulatory Know-How: Deep knowledge of global GMP and regulatory requirements for clinical and commercial drug substance facilities, plus proven success in regulatory inspections and product launches.- Education: Undergraduate degree in Science or Engineering.

Desirable Skills/Experience:- Advanced Education: MS, PhD, or MBA.- Self-Starter: Highly proactive and resourceful, motivated by both immediate operational needs and long-term strategic vision.- Innovator: Strong continuous improvement focus, applying process excellence and digital tools to optimize outcomes.- Business Acumen: Extensive understanding of manufacturing, engineering, logistics, inventory, and supply chain in GMP environments.- Communication: Skilled communicator, comfortable managing up, down, and across functions, and leading both written and oral presentations to diverse audiences.

Why AstraZeneca:Join a company that blends the energy of a cutting-edge biotech with the scale and stability of a global biopharma. You will work shoulder-to-shoulder with scientists, operators, data specialists, engineers, and quality leaders—unexpected teams in the same room unleashing bold thinking to solve real manufacturing challenges. Your work directly supports patients with serious and often rare conditions, giving purpose to every batch released. We back ambition with support: modern technology, investment in capability, and leaders who value kindness alongside high standards. Here, you can shape an operation built for today and ready for tomorrow, and see the impact of your leadership in the lives of patients and the growth of your career.

Call to Action:If you are ready to build a resilient, digitally enabled DS operation in Dublin and turn excellence into everyday performance, step forward and share your story with us today!

Date Posted

15-Jul-2026

Closing Date

21-Jul-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Apply Now

Refine Your Search

lead site reliability engineer jobs in dublin, d

BDS Manufacturing Operations Lead

Staff Technical Program Manager, Site Reliability Engineering

Network Development Manager, Frontier Networking

WPM C4 IR Module Engineer

Senior Java Developer - Coaching & Delivery

PLATFORM SUPPORT ENGINEER

Senior Network Engineer

Network Development Engineer, Network - Core

Senior Software Development Engineer

Critical Infrastructure Fire Protection Engineer (Field Engineering), Data Center Engineering

Warranty Technician

Automation Engineer - Utilities

Cloud Platform Lead

Senior Software Engineer - API Platform (Python/Typescript)

Engineering Manager - Civil, Structures & Utilities

Senior Developer, Agentic AI Engineering

Asset Management Utilities Engineering Technician(Plumber)

Sr. Automation Engineer - Packaging

Electrical Colocation Regional Engineer, Colo Regional Engineering

Director Cloud Platform

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